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CD4 Mouse anti-Human, APC, Clone: RPA-T4, BD
Mouse Monoclonal Antibody
$88.00 - $699.00
Specifications
Antigen | CD4 |
---|---|
Clone | RPA-T4 |
Applications | Flow Cytometry |
Classification | Monoclonal |
Conjugate | APC |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
BDB561840
|
BD Biosciences
561840 |
25 Tests |
Each for $88.00
|
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BDB561841
|
BD Biosciences
561841 |
500 Tests |
Each for $699.00
|
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Description
The RPA-T4 monoclonal antibody specifically binds to CD4, a 59 kDa single-chain transmembrane glycoprotein that is expressed on T-helper/inducer cell populations. CD4 is also expressed on thymocytes subsets and at lower levels on monocytes and macrophages. CD4 functions as a co-receptor in MHC class II-restricted antigen-induced T cell activation and as a receptor for human immunodeficiency viruses (HIV). This antibody binds to the D1 domain (CDR1 and CDR3 epitopes) of the CD4 antigen and reacts with approximately 80% of thymocytes and 45% of peripheral blood lymphocytes. RPA-T4 is capable of blocking HIV-1, gp120, and inhibits syncytium formation.
Specifications
CD4 | |
Flow Cytometry | |
APC | |
RUO | |
Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
Primary | |
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
RPA-T4 | |
Monoclonal | |
Mouse | |
Human | |
IgG1 κ | |
Affinity Purified |
For Research Use Only.
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