CD4 Mouse anti-Rat, V450, Clone: OX-35, BD
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 561579
The OX-35 clone has been reported to react with the CD4 antigen on most thymocytes, a subpopulation of mature T lymphocytes (i.e. MHC class II-restricted T cells, including most T helper cells), monocytes, macrophages, some dendritic cells, and microglia. CD4 is an antigen coreceptor on the T-cell surface that interacts with MHC class II molecules on antigen-presenting cells. It participates in T-cell activation through it's association with the T-cell receptor complex and protein tyrosine kinase Lck. The OX-35 clone has been reported to bind to a different epitope of CD4 than that recognized by the W3/25 and OX-38 clones.
The antibody is conjugated to BD Horizon™ V450, which has been developed for use in multicolor flow cytometry experiments and is available exclusively from BD Biosciences. It is excited by the Violet laser Ex max of 406nm and has an Em Max at 450 nm. Conjugates with BD Horizon™ V450 can be used in place of Pacific Blue™ conjugates.
|Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.|
|Cd4; CD4 antigen; p55; W3/25 antigen; T-cell surface glycoprotein CD4|
|Rat T-cell blasts|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
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