CD4 Mouse anti-Human, V450, Clone: RPA-T4, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 560345

Catalog No. BDB560345

Description

The RPA-T4 clone reacts with CD4, a 59kDa single-chain transmembrane glycoprotein (receptor for human immunodeficiency virus (HIV)) present on T-helper/inducer cell populations. This antibody binds to the D1 domain (CDR1 and CDR3 epitopes) of the CD4 antigen and reacts with approximately 80% of thymocytes and 45% of peripheral blood lymphocytes. CD4 is also present in low density on peripheral blood monocytes. RPA-T4 is capable of blocking HIV-1, gp120, and inhibits syncytium formation. The antibody is conjugated to BD Horizon™ V450, which has been developed for use in multicolor flow cytometry experiments and is available exclusively from BD Biosciences. It is excited by the Violet laser Ex max of 406nm and has an Em Max at 450nm. Conjugates with BD Horizon™ V450 can be used in place of Pacific Blue™ conjugates.

Host Species: Mouse
Clone: RPA-T4
Isotype: IgG1 κ
Species Reactivity: Human

Flow Cytometry, Functional Assay

Specifications

• Antigen: CD4
• Classification: Monoclonal
• Conjugate: Violet Fluor 450 (V450)
• Host Species: Mouse
• Quantity: 120 Tests
• Research Discipline: Immunology
• Target Species: Human
• Isotype: IgG1 κ

• Applications: Flow Cytometry
• Clone: RPA-T4
• Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

For Research Use Only.