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anti-CD40, Clone: 11E9, Epredia™ LabVision
Mouse Monoclonal Antibody
Supplier: Epredia MS1090PCS
Description
The CD40 antigen is a single chain glycoprotein. It is known to be a member of the tumour necrosis factor/nerve growth factor superfamily and shows a significant homology to the Hodgkin's disease-associated antigen, CD30. CD40 is present on all B cells except plasma cells. It is also found on some epithelial cells, carcinomas and lymphoid dendritic cells. The precise function of the CD40 antigen is unknown but it appears to be involved in the transduction of regulatory signals for cellular functions such as B cell proliferation and differentiation.
Host Species: Mouse
Clone: 11E9
Isotype: IgG2b
Cross Reactivity: Human. Others not-tested.
Epitope: Extracellular domain
Immunogen: Recombinant protein encoding the entire external domain of human CD40.
Molecular Weight: 44kDa
Positive Control: Hodgkin's lymphoma
Cellular Localization: Cell membrane
Immunohistochemistry (Formalin/Paraffin)
Specifications
| CD40 Ab-1 | |
| n/a | |
| Mouse | |
| Hodgkin's lymphoma | |
| Primary | |
| room temp |
| Monoclonal | |
| Unconjugated | |
| Recombinant protein encoding the entire external domain of human CD40. | |
| 5 Slides | |
| Human | |
| IgG2b |
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