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anti-CD40, Clone: 11E9, Epredia™ LabVision

Catalog No. MS1090S1 Shop All Epredia Products
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100 μL
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500 μL
7 mL
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Catalog No. Quantity
MS1090S1 500 μL
MS1090S0 100 μL
MS1090S 1 mL
MS1090R7 7 mL
MS1090PCS 5 Slides
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Catalog No. MS1090S1 Supplier Epredia Supplier No. MS1090S1

Description

Mouse Monoclonal Antibody

The CD40 antigen is a single chain glycoprotein. It is known to be a member of the tumour necrosis factor/nerve growth factor superfamily and shows a significant homology to the Hodgkin's disease-associated antigen, CD30. CD40 is present on all B cells except plasma cells. It is also found on some epithelial cells, carcinomas and lymphoid dendritic cells. The precise function of the CD40 antigen is unknown but it appears to be involved in the transduction of regulatory signals for cellular functions such as B cell proliferation and differentiation.

Host Species: Mouse
Clone: 11E9
Isotype: IgG2b
Cross Reactivity: Human. Others not-tested.
Epitope: Extracellular domain
Immunogen: Recombinant protein encoding the entire external domain of human CD40.
Molecular Weight: 44kDa
Positive Control: Hodgkin's lymphoma
Cellular Localization: Cell membrane

Immunohistochemistry (Formalin/Paraffin)

Abbreviations: AP=Affinity Purification, ChIP=Chromatin IP, CM=Confocal Microscopy, DB=Dot Blot, EIA=ELISA, EM=Electron Microscopy, FC=Flow Cytometry, GS=Gel Supershift, IC=Immunocytochemistry, IF=Immunofluorescence, IH=Immunohistology/Immunohistochemistry, IP=Immunoprecipitation, IPK=IP Kinase Assay, KA=Kinase Assay, NEUT=Neutralization, PIA=Peptide Inhibition Assay, RIA=Radioimmunossay, TCA=T Cell Activation, WB=Western Blotting, Species: Am=Amphibian, Av=Avian, B=Bovine, Ca=Cat ,Ck=Chicken, D=Dog, Dr=Deer, Ds=Drosophila, El=Elk, Fg=Frog, Fs=Fish, Ft=Ferret, G=Goat, Gp=Guinea Pig, H=Horse, Hm=Hamster, Hu=Human, K=Kangaroo, Ms=Mouse, Nhp=Non-Human Primate, O=Ovine, P=Porcine, Rb=Rabbit, Rp=Reptile, Rt=Rat, Ys=Yeast, Xn=Xenopus, (wk)=cross reacts weakly

Specifications

Antigen CD40 Ab-1
Classification Monoclonal
Concentration n/a
Conjugate Unconjugated
Host Species Mouse
Immunogen Recombinant protein encoding the entire external domain of human CD40.
Purification Method Hodgkin's lymphoma
Quantity 500 μL
Primary or Secondary Primary
Target Species Human
Content And Storage 2–8 degrees
Form Supernatant
Isotype IgG2b
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