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CD40 Mouse anti-Human, PE, Clone: 5C3, BD

Catalog No. BDB555589 Shop All BD Biosciences Products
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BDB555589 100 Tests
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Catalog No. BDB555589 Supplier BD Biosciences Supplier No. 555589
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Description

Mouse Monoclonal Antibody

This antibody reacts with a 45-48kDa type I integral membrane glycoprotein present on peripheral blood and tonsillar B cells, but not expressed on terminally differentiated B cells. CD40 is also present on some epithelial cells, carcinomas and lymphoid dendritic cells. This antibody is useful for studies of B-cell growth and function. Anti-CD40 antibodies have been reported to stimulated B-cell proliferation when costimulated with anti-μ, anti-CD20 antibodies or with phorbol esters. 5C3 is capable of inducing B-cell proliferation when presented with IL-4. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD40
Applications Flow Cytometry
Classification Monoclonal
Clone 5C3
Conjugate PE
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Purification Method Affinity Purified
Quantity 100 Tests
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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For Research Use Only.

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