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Description
Reacts with a calcium-dependent complex of CD41/CD61 (GPIIb/IIIa) expressed on normal platelets and megakaryocytes. CD41/CD61 complex is the receptor for fibrinogen, fibronectin and von Willebrand factor, and mediates platelet adhesion and aggregation. CD41 (clone HIP8) completely inhibits ADP-, epinephrine-, and collagen-induced platelet activation, and partially inhibits ristocetin- and thrombin-induced platelet activation. This antibody is useful in the morphological and physiological studies of platelets and megakaryocytes.
Specifications
Specifications
| Antigen | CD41a |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | HIP8 |
| Conjugate | FITC |
| Formulation | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | Purified platelet membrane glycoproteins |
| Purification Method | Affinity Purified |
| Quantity | 50 Tests |
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For Research Use Only.
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