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CD41a Mouse anti-Human, FITC, Clone: HIP8, BD

Catalog No. BDB561851 Shop All BD Biosciences Products
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BDB561851 25 Tests
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Catalog No. BDB561851 Supplier BD Biosciences Supplier No. 561851
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Description

Mouse Monoclonal Antibody

The HIP8 monoclonal antibody specifically binds to the α-chain of CD41. CD41 is also known as Integrin αIIb or Platelet GPIIb. The calcium-dependent complex of CD41 and CD61 (β3 integrin or GPIIIa) is normally expressed on platelets and megakaryocytes. The CD41/CD61 complex is the receptor for fibrinogen, fibronectin and von Willebrand factor, and mediates platelet adhesion and aggregation. CD41 (clone HIP8) completely inhibits ADP-, epinephrine-, and collagen-induced platelet activation, and partially inhibits ristocetin- and thrombin-induced platelet activation. This antibody is useful in the morphological and physiological studies of platelets and megakaryocytes.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD41a
Applications Flow Cytometry
Classification Monoclonal
Clone HIP8
Conjugate FITC
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Purified platelet membrane glycoproteins
Purification Method Affinity Purified
Quantity 25 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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