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CD42B Mouse anti-Human, NA/LE, Unlabeled, Clone: HIP1, BD

Catalog No. BDB562255 Shop All BD Biosciences Products
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BDB562255 0.5 mg
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Catalog No. BDB562255 Supplier BD Biosciences Supplier No. 562255
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Description

Mouse Monoclonal Antibody

The HIP1 monoclonal antibody specifically binds to CD42b. CD42b is also known as the Platelet glycoprotein Ib alpha chain that is encoded by the GP1BA gene. CD42b is disulfide bonded to CD42c to form a 170 kDa heterodimer, GPIb. GPIb forms a noncovalent complex with CD42a and CD42d (CD42 complex) that is expressed on platelets and megakaryocytes. The CD42 complex serves as the von Willebrand Factor(vWF) surface receptor involved in the adhesion of platelets to the subendothelium of damaged vascular walls. HIP1 inhibits the ristocetin-dependent binding ofvWF to platelets and partially inhibits collagen-induced aggregation.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD42b
Applications Flow Cytometry
Classification Monoclonal
Clone HIP1
Concentration 1.0mg/mL
Conjugate Unconjugated
Description GP1BA; GPIbalpha; GP-Ib alpha; GPIb-alpha; CD42b-alpha; Glycocalicin; BSS
Formulation No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Host Species Mouse
Purification Method Affinity Purified
Quantity 0.5 mg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C
Isotype IgG1 κ
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