CD43 (Ly-48, Leukosialin) Rat anti-Mouse, APC, Clone: S7, BD

Rat Monoclonal Antibody

Supplier:  BD Biosciences 560663

Catalog No. BDB560663

Description

The S7 monoclonal antibody specifically binds to the 115 kDa glycosylated form of CD43 (Ly-48, Leukosialin). CD43 is expressed on IL-7-responsive pro-B cells, plasma cells, peritoneal and splenic CD5+ B cells (B-1 cells), granulocytes, monocytes, macrophages, platelets, natural killer cells, thymocytes, peripheral T cytotoxic/suppressor cells, and most T helper cells, but not resting conventional peripheral B cells. CD43 expression has also been detected on pluripotent hematopoietic stem cells and myeloid, lymphoid, and NK-cell progenitors in the bone marrow. Studies of CD43-deficient mice indicate that CD43 participates in the negative regulation of T-cell activation and adhesion.

Specifications

• Antigen: CD43
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Description: Spn ; Sialophorin; Leukosialin; Ly-48; Ly48; Galgp; LEUK
• Host Species: Rat
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Applications: Flow Cytometry
• Clone: S7
• Conjugate: APC
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: Mouse plasmacytoma MOPC-315
• Quantity: 50 μg
• Research Discipline: Immunology
• Target Species: Mouse
• Isotype: IgG2a κ

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov