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CD43 (Ly-48, Leukosialin) Rat anti-Mouse, APC, Clone: S7, BD

Rat Monoclonal Antibody

Supplier:  BD Biosciences 560663

Catalog No. BDB560663


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Description

Description

The S7 monoclonal antibody specifically binds to the 115 kDa glycosylated form of CD43 (Ly-48, Leukosialin). CD43 is expressed on IL-7-responsive pro-B cells, plasma cells, peritoneal and splenic CD5+ B cells (B-1 cells), granulocytes, monocytes, macrophages, platelets, natural killer cells, thymocytes, peripheral T cytotoxic/suppressor cells, and most T helper cells, but not resting conventional peripheral B cells. CD43 expression has also been detected on pluripotent hematopoietic stem cells and myeloid, lymphoid, and NK-cell progenitors in the bone marrow. Studies of CD43-deficient mice indicate that CD43 participates in the negative regulation of T-cell activation and adhesion.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD43
Monoclonal
0.2mg/mL
Spn ; Sialophorin; Leukosialin; Ly-48; Ly48; Galgp; LEUK
Rat
Affinity Purified
RUO
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Flow Cytometry
S7
APC
Aqueous buffered solution containing ≤0.09% sodium azide.
Mouse plasmacytoma MOPC-315
50 μg
Immunology
Mouse
IgG2a κ
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