MilliporeSigma™ anti-CD44 Violer Fluor 450, Clone: IM7,

Catalog No.	Quantity
MABF1561MI	25 μg
MABF1562MI	100 μg

Catalog No. MABF1561MI Supplier MilliporeSigma™ Supplier No. MABF1561

Description

Rat Monoclonal Antibody

Specifically detects CD44 Clone: IM7 in Human, Mouse samples, and it is validated for Flow Cytometry

The IM7 antibody recognizes CD44, a ubiquitously expressed cell surface receptor which is important for extracellular matrix organization, cell-cell and cell-matrix adhesion and migration. CD44 may be expressed in a number of different isoforms (splice variants) from the most typical or 'standard' form, known as CD44s, to variants designated CD44v, e.g. CD44v1 or CD44v6. These receptors interact with several ligands, but most often associate with an extracellular matrix component hyaluronate, through which it mediates adhesion.The IM7 antibody may be used for detection of all isoforms of CD44, as it recognizes constant epitopes near the extracellular proximal domain. (Xu et al, 2002, J. Leukoc. Biol. 72:1133-1141). It has been reported to be cross-reactive with many non-human species including Baboon, Chimpanzee, Cynomolgus, Rhesus, Horse, Cow, Pig, Dog and Cat CD44.

Specifications

• Antigen: CD44
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: IM7
• Conjugate: Violet Fluor 450 (V450)
• Formulation: Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
• Gene Accession No.: P15379
• Gene Symbols: Cd44, Ly-24
• Host Species: Rat
• Immunogen: Proprietary immunogen
• Purification Method: Purified by size-exclusion chromatography
• Quantity: 25 μg
• Regulatory Status: RUO
• Research Discipline: Inflammation, Immunology
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Content And Storage: 2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
• Form: Purified

For Research Use Only