MilliporeSigma™ anti-CD44 Violer Fluor 710, Clone: IM7,

Rat Monoclonal Antibody

Supplier:  MilliporeSigma™ MABF1564

Catalog No. MABF1564MI

Description

Specifically detects CD44 Clone: IM7 in Human, Mouse samples, and it is validated for Flow Cytometry

The IM7 antibody recognizes CD44, a ubiquitously expressed cell surface receptor which is important for extracellular matrix organization, cell-cell and cell-matrix adhesion and migration. CD44 may be expressed in a number of different isoforms (splice variants) from the most typical or 'standard' form, known as CD44s, to variants designated CD44v, e.g. CD44v1 or CD44v6. These receptors interact with several ligands, but most often associate with an extracellular matrix component hyaluronate, through which it mediates adhesion.The IM7 antibody may be used for detection of all isoforms of CD44, as it recognizes constant epitopes near the extracellular proximal domain. (Xu et al, 2002, J. Leukoc. Biol. 72:1133-1141).

Specifications

• Antigen: CD44
• Classification: Monoclonal
• Conjugate: Violet Fluor 710 (V710)
• Gene Accession No.: P15379
• Host Species: Rat
• Purification Method: Purified by size-exclusion chromatography
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: 2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze

• Applications: Flow Cytometry
• Clone: IM7
• Formulation: Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
• Gene Symbols: Cd44, Ly-24
• Immunogen: Proprietary immunogen
• Quantity: 100 μg
• Research Discipline: Inflammation, Immunology
• Target Species: Human, Mouse
• Form: Purified

For Research Use Only