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CD45RC Rat anti-Mouse, PE, Clone: DNL-1.9, BD

Catalog No. BDB557357 Shop All BD Biosciences Products
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Catalog No. BDB557357 Supplier BD Biosciences Supplier No. 557357
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Description

Rat Monoclonal Antibody

The DNL-1.9 antibody reacts with an exon C-dependent epitope of CD45 protein which is found at high density on B cells, and at low density on peripheral T cytotoxic/suppressor cells, a subset of peripheral T helper cells, and a very small subset of thymocytes. CD45 is a member of the Protein Tyrosine Phosphatase (PTP) family: Its intracellular (COOHterminal) region contains two PTP catalytic domains, and the extracellular region is highly variable due to alternative splicing of exons 4, 5, and 6 (designated A, B, and C, respectively), plus differing levels of glycosylation. The CD45 isoforms detected in the mouse are cell type-, maturation-, and activation state-specific. The CD45 isoforms play complex roles in T-cell and B-cell antigen receptor signal transduction.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD45RC
Applications Flow Cytometry
Classification Monoclonal
Clone DNL-1.9
Concentration 0.2mg/mL
Conjugate PE
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen 70Z/3 mouse pre-B cell line
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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For Research Use Only.

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