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CD45RO Mouse anti-Human, PerCP-Cy5.5, Clone: UCHL1, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 560607

Catalog No. BDB560607


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Description

Description

The UCHL1 monoclonal antibody specifically binds to the 180 kDa isoform of CD45 (aka, the Leukocyte Common Antigen). CD45RO is a type I transmembrane glycoprotein that has cytoplasmic protein tyrosine phosphatase activity and functions in signal transduction pathways. This CD45 isoform does not include amino acid sequences encoded by the variable CD45 exons A, B, or C. CD45RO is expressed on most thymocytes, activated T cells, memory T cells, granulocytes and monocytes, but only on a proportion of resting T cells. CD45RO and CD45RA antibodies seem to define complementary, predominantly non-overlapping, populations in resting peripheral T cells, demonstrating heterogeneity within the CD8 and CD4 subpopulations. CD45RO binds to CD22.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD45RO
Monoclonal
PerCP-Cyanine5.5
Mouse
Affinity Purified
RUO
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Flow Cytometry
UCHL1
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Human IL-2-dependent T-cell line
50 Tests
Immunology
Human
IgG2a κ
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