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CD46 Mouse anti-Human, PE, Clone: E4.3, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 564252

Catalog No. BDB564252


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Description

Description

The E4.3 monoclonal antibody specifically binds to CD46. CD46 is also known as membrane cofactor protein (MCP). CD46 is a type I membrane glycoprotein composed of two non-disulfide linked α (66 kDa) and β (56 kDa) chains expressed on lymphocytes, monocytes and granulocytes. It is not expressed on erythrocytes or platelets. There are four isoforms of the dimer which function as complement regulatory factors. CD46 promotes the enzymatic degradation of activated C3b and/or C4b deposited on host cells. It also serves as the measles virus receptor.

Specifications

Specifications

CD46
E4.3
MCP; TLX
Affinity Purified
IgG2a, κ
RUO
Primary
Human
Flow Cytometry
PE
Aqueous buffered solution containing BSA and ≤0.09% sodium azide
Murine
100 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Documents
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