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CD46 Mouse anti-Human, PE, Clone: E4.3, BD

Catalog No. BDB564252 Shop All BD Biosciences Products
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Catalog No. BDB564252 Supplier BD Biosciences Supplier No. 564252
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Mouse Monoclonal Antibody

The E4.3 monoclonal antibody specifically binds to CD46. CD46 is also known as membrane cofactor protein (MCP). CD46 is a type I membrane glycoprotein composed of two non-disulfide linked α (66 kDa) and β (56 kDa) chains expressed on lymphocytes, monocytes and granulocytes. It is not expressed on erythrocytes or platelets. There are four isoforms of the dimer which function as complement regulatory factors. CD46 promotes the enzymatic degradation of activated C3b and/or C4b deposited on host cells. It also serves as the measles virus receptor.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD46
Applications Flow Cytometry
Classification Monoclonal
Clone E4.3
Conjugate PE
Description MCP; TLX
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide
Host Species Mouse
Purification Method Affinity Purified
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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