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Description
The Ha31/8 antibody reacts with the 180kDa integrin α1 chain (CD49a), which is a transmembrane glycoprotein that non-covalently associates with the integrin β1 subunit (CD29) to form the α1β1 (complex known as VLA-1). VLA-1 has been reported to be expressed on activated T cells, monocytes, smooth muscle cells, and endothelial cells. It is a receptor for collagen and laminin. The Ha31/8 monoclonal antibody is specific for both rat1 and mouse CD49a. It has been reported that Ha31/8 antibody can block VLA-1-mediated binding of rat cells to collagen.
Specifications
Specifications
| Antigen | CD49a |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | HA31/8 |
| Concentration | 1.0mg/mL |
| Conjugate | Unconjugated |
| Description | Itga1; Integrin alpha-1; Integrin α1; Laminin and collagen receptor; VLA-1a |
| Formulation | No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay. |
| Host Species | Hamster |
| Immunogen | Rat Emulsified Lewis Rat Glomeruli Cells |
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Safety and Handling
For Research Use Only.
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