CD49b Mouse anti-Human, PE-CF594, Clone: 12F1, BD
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 564121
The 12F1 monoclonal antibody specifically binds to the integrin α 2 chain (VLA- α 2), a member of the integrin family of extracellular matrix and cell-cell adhesion receptors. VLA- α 2 is non-covalently associated with VLA- β 1 chain (CD29) in the VLA-2 complex. α 2 is expressed on numerous cell types including activated T cells, platelets, and long-term cultivated T cells. α 2β
This antibody is conjugated to BD Horizon PE-CF594, which has been developed exclusively by BD Biosciences as a better alternative to PE-Texas Red. PE-CF594 excites and emits at similar wavelengths to PE-Texas Red yet exhibits improved brightness and spectral characteristics. Due to PE having maximal absorption peaks at 496nm and 564nm, PE-CF594 can be excited by the blue (488-nm), green (532-nm) and yellow-green (561-nm) lasers and can be detected with the same filter set as PE-Texas Red (eg 610/20-nm filter).
|Integrin α2 chain; ITGA2; VLA-2 alpha; Platelet GPIa; Collagen receptor; BR|
|Aqueous buffered solution containing BSA and ≤0.09% sodium azide.|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
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