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CD49b Mouse anti-Human, PE-CF594, Clone: AK-7, BD

Catalog No. BDB564317 Shop All BD Biosciences Products
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100 Tests
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BDB564317 100 Tests
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Catalog No. BDB564317 Supplier BD Biosciences Supplier No. 564317

Description

Mouse Monoclonal Antibody

The AK-7 monoclonal antibody specifically binds to CD49b. CD49b is also known as integrin α2 chain, VLA-α2, and GP1a. CD49b is a type I transmembrane glycoprotein and be longs to the integrin family of extracellular matrix and cell-cell adhesion receptors. CD49b is expressed on numerous cell types including platelets, activated T cells, B cells, and monocytes. CD49b noncovalently associates with CD29 to form the VLA-2 complex (integrin α 2/ β 1). The VLA-2 complex serves as a receptor for collagen and laminin. It can regulate responses mediated by proinflammatory effector cells.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD49b
Applications Flow Cytometry
Classification Monoclonal
Clone AK-7
Conjugate PE-CF594
Description Integrin α2 chain; VLA-α2: GP1a
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide
Host Species Mouse
Purification Method Affinity Purified
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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