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Description
Reacts with α 3 integrin, a 150 kDa transmembrane glycoprotein which non-covalently associates with integrin β 1 (CD29) to form the α 3β 1 (CD49c/CD29, VLA-3) complex. CD49c is expressed mostly on endothelial and epithelial cells (basal epidermal layers). It is not expressed on platelets and is expressed weakly on peripheral blood leukocytes. The CD49c/CD29 complex serves as an adhesive receptor for kalinin or epiligrin. This interaction may be important for thymocyte interaction with thymic epithelium.
Specifications
Specifications
| Antigen | CD49c |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | C3 II.1 |
| Conjugate | PE |
| Description | Integrin α3 chain |
| Formulation | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| Host Species | Mouse |
| Purification Method | Affinity Purified |
| Quantity | 100 Tests |
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