CD49c Mouse anti-Human, PE, Clone: C3 II.1, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 556025

Catalog No. BDB556025

Description

Reacts with α 3 integrin, a 150 kDa transmembrane glycoprotein which non-covalently associates with integrin β 1 (CD29) to form the α 3β 1 (CD49c/CD29, VLA-3) complex. CD49c is expressed mostly on endothelial and epithelial cells (basal epidermal layers). It is not expressed on platelets and is expressed weakly on peripheral blood leukocytes. The CD49c/CD29 complex serves as an adhesive receptor for kalinin or epiligrin. This interaction may be important for thymocyte interaction with thymic epithelium.

Specifications

• Antigen: CD49c
• Classification: Monoclonal
• Conjugate: PE
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Applications: Flow Cytometry
• Clone: C3 II.1
• Description: Integrin α3 chain
• Host Species: Mouse
• Quantity: 100 Tests
• Research Discipline: Immunology
• Target Species: Human
• Isotype: IgG1 κ

For Research Use Only.