CD49d Rat anti-Mouse, Alexa Fluor 647, Clone: R1-2, BD

Rat Monoclonal Antibody

Supplier:  BD Biosciences 564394

Catalog No. BDB564394

Description

The R1-2 antibody reacts with the integrin α 4 chain (CD49d), which is expressed as a heterdimer with either of two β , β 1 or β 7 (also known as β p). The α 4β α 4β 7 also preferentially binds to the mucosal vascular addressin, MAdCAM-1. The R1-2 antibody blocks some α 4 integrin-mediated binding functions. In combination with mAb 9C10 (MFR4.B) (Cat. No. 553313), binding of VLA-4 expressing cells to VCAM-1 can be almost completely inhibited.

Specifications

• Antigen: CD49d
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Description: Integrin α4 chain
• Host Species: Rat
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Mouse
• Isotype: IgG2b κ

• Applications: Flow Cytometry
• Clone: R1-2
• Conjugate: Alexa Fluor 647
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: AKR/Cum mouse spontaneous T lymphoma line TK1
• Quantity: 100 μg
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.