CD49d Rat anti-Mouse, Alexa Fluor 647, Clone: R1-2, BD
Rat Monoclonal Antibody
Manufacturer: BD Biosciences 564394
The R1-2 antibody reacts with the integrin α 4 chain (CD49d), which is expressed as a heterdimer with either of two β , β 1 or β 7 (also known as β p). The α 4β α 4β 7 also preferentially binds to the mucosal vascular addressin, MAdCAM-1. The R1-2 antibody blocks some α 4 integrin-mediated binding functions. In combination with mAb 9C10 (MFR4.B) (Cat. No. 553313), binding of VLA-4 expressing cells to VCAM-1 can be almost completely inhibited.
|Alexa Fluor 647|
|Aqueous buffered solution containing ≤0.09% sodium azide.|
|CDF IgG2b, κ|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
|Integrin α4 chain|
|AKR/Cum mouse spontaneous T lymphoma line TK1|
|The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.|
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