Learn More
Description
The 9F10 monoclonal antibody specifically reacts with the integrin α 4 chain, that is expressed as a heterodimer with either of two β integrin subunits, β 1 (CD29) or β 7. The α 4β 1 integrin (VLA-4) is expressed on lymphocytes, monocytes, thymocytes, NK cells, and several B- and T-cell lines, and mediates binding to VCAM-1 (CD106) and the CS-1 region of fibronectin. The α β 7 also binds fibronectin and VCAM-1, and has been shown in the mouse to preferentially bind the mucosal vascular addressin molecule, MAdCAM-1. This antibody is useful for studies of the expression by and function of cells that express α 4 chain-containing integrins.
Specifications
Specifications
| Antigen | CD49d |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | 9F10 |
| Conjugate | Brilliant Violet 711 |
| Description | Integrin α4 chain; Integrin alpha 4; ITGA4; IA4; alpha 4 subunit of VLA-4 |
| Formulation | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| Host Species | Mouse |
| Purification Method | Affinity Purified |
| Quantity | 50 Tests |
| Show More |
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.