CD49d Mouse anti-Human, Unlabeled, Clone: 9F10, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 555502

Catalog No. BDB555502

Description

Reaacts with the integrin α4 chain, which is expressed as a heterodimer with either of two β subunits, β1 (CD29) or β7. The α4β 1 integrin (VLA-4) is expressed on lymphocytes, monocytes, thymocytes, NK cells, and several B- and T-cell lines, and mediates binding to VCAM-1 (CD106) and the CS-1 region of fibronectin. The α4β7 integrin has a similar tissue distribution, except it is found on only a small subpopulation of thymocytes. Integrin α4β7 also binds fibronectin and VCAM-1, and has been shown in the mouse to preferentially bind the mucosal vascular addressin molecule, MAdCAM-1. This antibody is useful for studies of the expression and function of a4 chain-containing integrins. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Specifications

• Antigen: CD49d
• Classification: Monoclonal
• Concentration: 0.5mg/mL
• Description: Integrin α4 chain; Integrin alpha 4; ITGA4; IA4; alpha 4 subunit of VLA-4
• Host Species: Mouse
• Quantity: 0.1 mg
• Research Discipline: Immunology
• Target Species: Baboon, Bovine, Canine, Cynomolgus, Equine, Feline, Human, Rhesus Monkey, Sheep
• Isotype: IgG1 κ

• Applications: Flow Cytometry
• Clone: 9F10
• Conjugate: Unconjugated
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C

For Research Use Only.