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CD49d Rat anti-Mouse, PE, Clone: R1-2, BD

Catalog No. BDB553157 Shop All BD Biosciences Products
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0.2 mg
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BDB553157 0.2 mg
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Catalog No. BDB553157 Supplier BD Biosciences Supplier No. 553157

Description

Rat Monoclonal Antibody

The R1-2 antibody reacts with the integrin α4 chain (CD49d), which is expressed as a heterdimer with either of two β, β1 or β7 (also known as βp). The α4βα4β7 also preferentially binds to the mucosal vascular addressin, MAdCAM-1. The R1-2 antibody blocks some α4 integrin-mediated binding functions. In combination with mAb 9C10 (MFR4.B) (Cat. No. 553313), binding of VLA-4 expressing cells to VCAM-1 can be almost completely inhibited.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD49d
Applications Flow Cytometry
Classification Monoclonal
Clone R1-2
Concentration 0.2mg/mL
Conjugate PE
Description Integrin α4 chain
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen AKR/Cum mouse spontaneous T lymphoma line TK1
Purification Method Affinity Purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2b κ
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For Research Use Only.

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