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Description
The 5H10-27 (MFR5) antibody reacts with the α5 chain of the integrin α5β1 fibronectin receptor (CD49e/CD29, VLA-5) on thymocytes, activated T lymphocytes, mast cells, and a variety of mouse cell lines, but not splenocytes. Soluble 5H10-27 (MFR5) antibody has been reported to inhibit VLA-5–mediated functions in vitro. In addition, immobilized mAb 5H10-27 (MFR5) has been demonstrated to costimulate the proliferative response of CD8+ T cells to plate-bound anti-CD3e antibody.
Specifications
Specifications
| Antigen | CD49e |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | 5H10-27 |
| Concentration | 0.5mg/mL |
| Conjugate | Biotin |
| Description | Integrin α5 chain |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Host Species | Rat |
| Immunogen | Mouse Mast Cell Line MC/9 |
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For Research Use Only.
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