CD49e Mouse anti-Human, NA/LE, Unlabeled, Clone: IIA1, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 555614

Catalog No. BDB555614

Description

Reacts with the α5 integrin, a dimer of 135/25kDa, that associates with β1 integrin (CD29) to form VLA-5, a well-established fibronectin receptor that is expressed on many cell types, including fibroblasts, endothelial cells, epithelial cells, platelets, peripheral T cells, the myeloid cell line U937, K562 and some melanoma cell lines. This clone inhibits α5β1/ligand binding, and is useful for studies of the expression and function of this integrin. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Specifications

• Antigen: CD49e
• Classification: Monoclonal
• Concentration: 1.0mg/mL
• Description: Integrin α5 Chain
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C

• Applications: Flow Cytometry
• Clone: IIA1
• Conjugate: Unconjugated
• Formulation: No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
• Immunogen: Human α5β1 Protein
• Quantity: 0.5 mg
• Research Discipline: Immunology
• Target Species: Human
• Isotype: IgG1 κ

For Research Use Only.