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Description
The OX-19 antibody reacts with CD5, a 69 kDa cell-surface glycoprotein found on thymocytes, peripheral T lymphocytes, and some thymic dendritic cells, but not on alloantigen-activated cytotoxic T cells, NK cells, γδ TCR-bearing intestinal intraepithelial lymphocytes, or dendritic epidermal T cells. A CD5+ subset of B lymphocytes has not been characterized in the rat. In the mouse and human, CD72 is the major ligand for CD5. While the OX-19 antibody is not mitogenic, its presence augments in vitro proliferative responses of T cells to lectins and allogeneic cells.
This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.
Specifications
Specifications
| Antigen | CD5 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | OX-19 |
| Concentration | 0.5mg/mL |
| Conjugate | FITC |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | Rat Thymocyte Lentil Lectin-binding Glycoproteins |
| Purification Method | Affinity Purified |
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Safety and Handling
For Research Use Only.
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