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CD51 Rat anti-Mouse, PE, Clone: RMV-7, BD

Catalog No. BDB551187 Shop All BD Biosciences Products
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Catalog No. BDB551187 Supplier BD Biosciences Supplier No. 551187
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Description

Rat Monoclonal Antibody

The rat anti-mouse CD51 (clone RMV-7) antibody reacts with the 140 kDa integrin αV chain. Heterodimers of CD51 with several integrin β chains function as receptors for extracellular matrix proteins. CD51/CD61 (αVβ3 integrin, vitronectin receptor) mediates adhesion to fibronectin, fibrinogen, vitronectin, thrombospondin, von Willebrand factor, and CD31 (PECAM-1). It has been reported to be expressed on activated T lymphocytes, polymorphonuclear granulocytes, blastocysts, and osteoclasts. CD51 has reportedly been found to be undetectable on mouse platelets using either antibody clones H9.2B8 or RMV-7. CD51 also forms heterodimers with CD29 (integrin β1), integrins β5, β

This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD51
Applications Flow Cytometry
Classification Monoclonal
Clone RMV-7
Concentration 0.2mg/mL
Conjugate PE
Description Integrin αV chain
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen Mouse (BALB/c) IL-2-activated killer (LAK) Cells
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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For Research Use Only.

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