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CD56 Mouse anti-Human, Unlabeled, Clone: NCAM16.2, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 559043

Catalog No. BDB559043


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Description

Description

The NCAM16.2 monoclonal antibody specifically binds to human CD56. It recognizes an extracellular immunoglobulin-like domain common to 120, 140, and 180 kDa forms of CD56, also known as the neural cell adhesion molecule (NCAM), NKH1 or MSK39. The CD56 antigen is expressed on approximately 10% to 25% of peripheral blood lymphocytes. It is present on essentially all resting and activated CD16+ natural killer (NK) lymphocytes and approximately 5% of CD3+ peripheral blood lymphocytes. CD3+ CD56+ T lymphocytes comprise a unique subset of cytotoxic T lymphocytes that mediates non-major histocompatibility complex (MHC)-restricted cytotoxicity. CD56 antigen density on NK lymphocytes increases upon cellular activation. The CD56 antigen is involved in neuronal homotypic cell adhesion and cell differentiation during embryogenesis. CD16+ CD56+ NK cells demonstrate reciprocal transfer of an activation state with dendritic cells.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD56
Monoclonal
1.0mg/mL
NCAM1; NCAM-1; NCAM; Leu-19; Neural cell adhesion molecule 1; NKH1; MSK39
Mouse
Affinity Purified
RUO
Primary
Store undiluted at 4°C
Flow Cytometry
NCAM16.2
Unconjugated
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunoaffinity-enriched adult human brain NCAM
0.2 mg
Immunology
Human
IgG2b κ
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