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Description
Anti-HNK-1 monoclonal antibody recognizes a 110 kD glycoprotein (CD57) that is expressed on a subset of natural killer (NK) lymphocytes and T lymphocytes. It also recognizes epitopes on neural or neuroectodermal tumors including neurofibromas, malignant melanomas, malignant peripheral neuroectodermal tumors, Ewing's sarcomas, and small-cell lung carcinomas. Anti-HNK-1 monoclonal antibody also recognizes a carbohydrate epitope on subpopulations of several cell-adhesion molecules including N-CAM and myelin-associated glycoprotein (MAG).
Specifications
Specifications
| Antigen | CD57 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | HNK-1 |
| Concentration | 1.0mg/mL |
| Conjugate | Unconjugated |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | Membrane extracts of the HSB-2 T-lymphoblastoid cell line |
| Purification Method | Affinity Purified |
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