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Description
The NK-1 monoclonal antibody specifically reacts with a 110 kDa carbohydrate antigen associated with myelin-associated glycoprotein expressed on 7-35% of normal peripheral blood lymphocytes including a subset of natural killer cells, a subset of CD8-positive peripheral blood T cells, and on some neural tissues. CD57 is not expressed on granulocytes, platelets, red blood cells or thymocytes. The function of CD57 is still unclear, however, its expression on T-cell subets occurs in late immune responses.
This antibody is conjugated to BD Horizon™ PE-CF594, which has been developed exclusively by BD Biosciences as a better alternative to PE-Texas Red™. PE-CF594 excites and emits at similar wavelengths to PE-Texas Red™ yet exhibits improved brightness and spectral characteristics. Due to PE having maximal absorption peaks at 496nm and 564nm, PE-CF594 can be excited by the blue (488-nm), green (532-nm) and yellow-green (561-nm) lasers and can be detected with the same filter set as PE-Texas Red™ (eg 610/20-nm filter).
Specifications
Specifications
| Antigen | CD57 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | NK-1 |
| Conjugate | PE-CF594 |
| Description | B3GAT1; Beta-1,3-glucuronyltransferase 1; HNK1; LEU7; NK-1; GLCATP; GLCUATP |
| Formulation | Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide. |
| Host Species | Mouse |
| Purification Method | Affinity Purified |
| Quantity | 100 Tests |
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