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CD59 Mouse anti-Rat, APC, Clone: TH9, BD

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BDB562103 50 μg
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Catalog No. BDB562103 Supplier BD Biosciences Supplier No. 562103
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Description

Mouse Monoclonal Antibody

The TH9 antibody monoclonal antibody specifically binds to CD59, a 21 kDa glycosyl-phosphatidyl inositol-anchored cell-surface glycoprotein of the Ly-6 superfamily. CD59 is expressed by many types of non-hematopoietic cells. In the rat hematopoietic system, CD59 has been detected on erythrocytes, monocytes, and some lymphocytes, but not on platelets. Soluble CD59 is found in body fluids and urine. CD59 is a complement regulatory protein that acts late in the complement cascade to prevent formation of the membrane attack complex (MAC). Therefore, CD59 is one of several proteins whose function is to protect host tissue from complement attack. Rat CD59 binds rat and human complement components and inhibits cytolysis mediated by complement from multiple species. CD59 has also been suggested to be a ligand for CD2 and to participate in T-cell costimulation.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD59
Applications Flow Cytometry
Classification Monoclonal
Clone TH9
Concentration 0.2mg/mL
Conjugate APC
Description MACIF; Membrane attack complex inhibition factor; Protectin
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Membrane attack complex-inhibitory proteins from Rat erythrocyte membranes
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Rat
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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