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CD61 Mouse anti-Rat, Unlabeled, Clone: F11, BD

Catalog No. BDB554951 Shop All BD Biosciences Products
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BDB554951 0.5 mg
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Catalog No. BDB554951 Supplier BD Biosciences Supplier No. 554951
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Description

Mouse Monoclonal Antibody

The F11 antibody reacts with the integrin β3 chain (CD61), which associates with the integrin αv chain (CD51), to form the vitronectin receptor found on endothelial cells, myeloid cells, and osteoclasts, and with the αIIb chain (CD41) on platelets and megakaryocytes. Both receptors mediate adhesion to fibronectin, fibrinogen, vitronectin, thrombospondin, and von Willebrand factor. F11 mAb has been reported to block the in vitro attachment of osteoclasts to several ligands. Weak reactivity with human osteoclasts, megakaryocytes, and platelets has also been observed. Other reported applications include immunoprecipitation, in vitro blocking, and immunohistochemical staining (IHC) of acetone-fixed frozen and zinc-fixed paraffin-embedded sections. IHC of formalin-fixed paraffin-embedded sections is not recommended.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD61
Applications Flow Cytometry
Classification Monoclonal
Clone F11
Concentration 0.5mg/mL
Conjugate Unconjugated
Description Integrin β3 chain
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Rat bone cell suspensions
Purification Method Affinity Purified
Quantity 0.5 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Rat
Content And Storage Store undiluted at 4°C
Isotype IgG1 κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.

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