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Description
The RB40.34 antibody reacts with mouse P-selectin (CD62P), a 140kDa protein which is expressed on activated platelets, activated endothelial cells, and megakaryocytes. P-selectin mediates the adhesion of neutrophils and monocytes to activated platelets and endothelial cells, mediates leukocyte rolling, and is involved in the migration of leukocytes into inflamed tissues. CD24 and CD162 (PSGL-1) are ligands of CD62P. mAb RB40.34 can block mouse P-selectin binding to its ligands in vitro and in vivo. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.
Specifications
Specifications
| Antigen | CD62P |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | RB40.34 |
| Concentration | 1.0mg/mL |
| Conjugate | Unconjugated |
| Description | P-selectin; Selp; LECAM3; LYAM3; PADGEM; GMP-140; Grmp |
| Formulation | No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay. |
| Host Species | Rat |
| Immunogen | P-selectin-IgG1 Fusion |
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For Research Use Only.
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