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CD63 Mouse anti-Rat, Unlabeled, Clone: AD1, BD

Catalog No. BDB551458 Shop All BD Biosciences Products
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BDB551458 0.1 mg
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Catalog No. BDB551458 Supplier BD Biosciences Supplier No. 551458
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Description

Mouse Monoclonal Antibody

The AD1 antibody reacts with a 50-60-kDa protein that is a homolog (87%) ofhuman CD63 (melanomaassociated antigen ME491). CD63, a highly glycosylated type-III lysosomal glycoprotein, is a member of the tetraspan transmembrane 4 superfamily (TM4SF) that also includes CD9, CD37, and CD53. In the rat, CD63 is expressed on mast cells and platelets. CD63 is also found on rat embryonic fibroblasts and hepatic cell, along with cultured cell lines of diverse origin (eg, liver, lung, and heart). Expression is upregulated with culture. CD63 is expressed in close proximity to the FcεRI on rat mast cells and has been shown to partially inhibit IgE-mediated histamine release. The function of CD63 has not been fully characterized.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD63
Applications Flow Cytometry
Classification Monoclonal
Clone AD1
Concentration 0.5mg/mL
Conjugate Unconjugated
Description ME491
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Rat basophilic leukemia cell line
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Rat
Content And Storage Store undiluted at 4°C
Isotype IgG1 κ
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For Research Use Only.

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