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CD64 Mouse anti-Human, NA/LE, Unlabeled, Clone: 10.1, BD

Catalog No. BDB562162 Shop All BD Biosciences Products
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BDB562162 0.5 mg
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Catalog No. BDB562162 Supplier BD Biosciences Supplier No. 562162
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Description

Mouse Monoclonal Antibody

The 10.1 monoclonal antibody specifically binds to CD64, a 72 kDa type I transmembrane glycoprotein that is a high affinity receptor for human IgG (FcγRI), especially the IgG1 and IgG3 subclasses. CD64 is expressed on monocytes, macrophages, dendritic cells, granulocytes activated with interferon-gamma and early myeloid lineage cells. CD64 associates with a signaling FcRγ homodimer to form the functional high affinity FcγRI complex. CD64 functions in both innate and adaptive immune responses and mediates endocytosis, phagocytosis, antigen presentation, antibody-dependent cellular toxicity, cytokine release and superoxide generation.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD64
Applications Flow Cytometry
Classification Monoclonal
Clone 10.1
Concentration 1.0mg/mL
Conjugate Unconjugated
Description FCGR1; FcRI; Fc-gamma RI; IgG Fc Receptor I; High affinity IgG FcR1
Formulation No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Host Species Mouse
Immunogen Human rheumatoid synovial fluid cells and fibronectin-purified monocytes
Purification Method Affinity Purified
Quantity 0.5 mg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C
Isotype IgG1 κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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