CD68 Mouse anti-Human, Brilliant Violet 421, Clone:  Y1/82A, BD

Catalog No.	Quantity
BDB564943	50 Tests

Catalog No. BDB564943 Supplier BD Biosciences Supplier No. 564943

Description

Mouse Monoclonal Antibody

The Y1/82A monoclonal antibody specifically binds to CD68 which is also known as, Scavenger receptor class D member 1 (SCARD1), Macrosialin, or GP110. CD68 is a cell surface 110 kDa-type I-transmembrane glycoprotein that is primarily expressed in cytoplasmic granules of monocytes, macrophages, dendritic cells, granulocytes, myeloid progenitor cells and, reportedly, a subset of CD34-positive hemopoietic bone marrow progenitor cells. CD68 belongs to the sialomucin family and serves as a scavenger receptor that can bind and internalize oxidized low density lipoproteins (LDL). This antibody is useful in studies of myeloid cell development and function.

The antibody was conjugated to BD Horizon BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter). BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.

Specifications

• Antigen: CD68
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone:  Y1/82A
• Conjugate: Brilliant Violet 421
• Description: GP110; Macrosialin; SCARD1; Scavenger receptor class D, member 1
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide
• Host Species: Mouse
• Immunogen: PHA-stimulated Human PBMC
• Purification Method: Affinity Purified
• Quantity: 50 Tests
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
• Isotype: IgG2b κ

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov