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CD73 Mouse anti-Human, PE-Cy7, Clone: AD2, BD

Catalog No. BDB561258 Shop All BD Biosciences Products
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Catalog No. BDB561258 Supplier BD Biosciences Supplier No. 561258
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Mouse Monoclonal Antibody

The AD2 monoclonal antibody specifically binds to ecto-5’-nucleotidase, a 70 kDa, glycosyl phosphatidylinositol (GPI)-anchored glycoprotein. CD73 is expressed on subsets of T and B lymphocytes, follicular dendritic cells, epithelial cells, endothelial cells and mesenchymal stem cells. Its expression on lymphocytes increases during T and B cell development. CD73 has enzymatic activity and catalyzes the dephosphorylation of adenosine monophosphate (AMP) converting it to adenosine. It has been suggested that CD73 can mediate costimulatory signals in T cell activation and adhesion of lymphocytes to endothelium.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD73
Applications Flow Cytometry
Classification Monoclonal
Clone AD2
Conjugate PE-Cyanine7
Description NT5E; 5' nucleotidase; 5'-NT; E5NT; Ecto-5'-nucleotidase; eN; eNT; NT; NT5
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Pre-B leukemia cell line
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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