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CD74 Rat anti-Mouse, Unlabeled, Clone: IN-1, BD

Catalog No. BDB555317 Shop All BD Biosciences Products
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BDB555317 0.5 mg
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Catalog No. BDB555317 Supplier BD Biosciences Supplier No. 555317
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Rat Monoclonal Antibody

The In-1 antibody reacts with CD74, the MHC class II-associated Invariant chain (Ii), expressed in I-A+ cell populations. Although it is predominantly expressed intracellularly, it has also been detected on the cell surface of some B-cell lines and at low levels on a small number of B lymphocytes. In the mouse, alternatively spliced transcripts encode 31-kDa and 41-kDa isoforms, and the cell-surface CD74 has a chondroitin sulfate side chain which allows it to interact with CD44. CD74 is directly involved in the intracellular transport of MHC class II molecules and antigen presentation, and it affects the maturation of T and B lymphocytes.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD74
Applications Flow Cytometry
Classification Monoclonal
Clone IN-1
Concentration 0.5mg/mL
Conjugate Unconjugated
Description Ii
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen ATL mouse lymphocytes and B10A mouse-derived CH1 B-cell lymphoma
Purification Method Affinity Purified
Quantity 0.5 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C
Isotype IgG2b κ
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For Research Use Only.

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