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CD74 Mouse anti-Human, Unlabeled, Clone: LN2, BD

Catalog No. BDB555612 Shop All BD Biosciences Products
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Catalog No. BDB555612 Supplier BD Biosciences Supplier No. 555612
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Mouse Monoclonal Antibody

Reacts with the cell surface MHC class II-associated invariant chain molecule (41, 35, 33 kDa). CD74 is moderately expressed on B cells, and weakly on monocytes and macrophages. Other reactive cells include Langerhans cells, dendritic cells, a subset of activated T cells and thymic epithelium. LN2 monoclonal antibody labels a nuclear membrane protein of follicular center and mantle zone B cells and a cytoplasmic protein of cells which bind HLA class II antibodies. CD74 is postulated to play a role in antigen processing and presentation through intracellular transport and expression of class II molecules on the cell surface. This antibody is suitable for staining formalin-fixed, paraffin-embedded tissue sections without citrate pretreatment.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD74
Applications Flow Cytometry
Classification Monoclonal
Clone LN2
Concentration 0.5mg/mL
Conjugate Unconjugated
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C
Isotype IgG1 κ
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For Research Use Only.

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