CD79b Mouse anti-Human, Unlabeled, Clone: SN8, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 557592

Catalog No. BDB557592

Description

Immunoglobulin (Ig) antigen receptors are composed of a non-covalently-associated complex of Ig and two other proteins, Ig α and Ig β , clustered as CD79a and CD79b, respectively. CD79b is a membrane glycoprotein of 229 residues, with a predicted relative molecular mass of 36-40 kDa. Its expression is restricted to B lineage cells, has been reported to associate with surface IgM receptor, and may be involved in signal transduction.

Antibody 3A2-2E7 (also known as SN8) was generated by immunization of cell membrane preparations from B-prolymphocytic leukemia cells. It has similar reactivity characteristics as clone CB3-1 (another CD79b available from BD Biosciences Pharmingen, Cat. No. 555678). Antibodies CD3-1 and 3A2-2E7 reacts with an epitope that is enhanced on certain B-cell leukemias such as prolymphocytic leukemia and lymphoma, but not on chronic lymphocytic leukemia.

This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Specifications

• Antigen: CD79b
• Classification: Monoclonal
• Concentration: 0.5mg/mL
• Description: Igβ/SN8/3A2-2E7-1F5
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C

• Applications: Flow Cytometry
• Clone: SN8
• Conjugate: Unconjugated
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: Cell membranes from human B-prol ymphocytic leukemia (B-PLL) cells
• Quantity: 0.1 mg
• Research Discipline: Immunology
• Target Species: Human
• Isotype: IgG1 κ

For Research Use Only.