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CD79b Mouse anti-Human, PE, Clone: SN8, BD

Catalog No. BDB557931 Shop All BD Biosciences Products
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BDB557931 100 Tests
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Catalog No. BDB557931 Supplier BD Biosciences Supplier No. 557931
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Description

Mouse Monoclonal Antibody

Immunoglobulin (Ig) antigen receptors are composed of a non-covalently-associated complex of Ig and two other proteins, Igα and Igβ, clustered as CD79a and CD79b, respectively. CD79b is a membrane glycoprotein of 229 residues, with a predicted relative molecular mass of 36-40 kDa. Its expression is restricted to B lineage cells, has been reported to associate with surface IgM receptor, and may be involved in signal transduction.

Antibody 3A2-2E7 (also known as SN8) was generated by immunization of cell membrane preparations from B-prolymphocytic leukemia cells. It has similar reactivity characteristics as clone CB3-1 (another CD79b available from BD Biosciences Pharmingen, Cat. No. 555678). Antibodies CD3-1 and 3A2-2E7 reacts with an epitope that is enhanced on certain B-cell leukemias such as prolymphocytic leukemia and lymphoma, but not on chronic lymphocytic leukemia.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD79b
Applications Flow Cytometry
Classification Monoclonal
Clone SN8
Conjugate PE
Description Igβ/SN8/3A2-2E7-1F5
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Cell membranes from human B-prol ymphocytic leukemia (B-PLL) cells
Purification Method Affinity Purified
Quantity 100 Tests
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.

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