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CD80 Mouse anti-Rat, Biotin, Clone: 3H5, BD

Catalog No. BDB555013 Shop All BD Biosciences Products
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BDB555013 0.5 mg
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Catalog No. BDB555013 Supplier BD Biosciences Supplier No. 555013

Description

Mouse Monoclonal Antibody

The 3H5 antibody reacts with CD80 (B7-1), a member of the Ig superfamily of transmembrane proteins. CD80, a ligand for CD28 and CD152 (CTLA-4), is one of the accessory molecules that plays an important role in T cell-B cell costimulatory interactions. CD80 is predominantly expressed on antigen-presenting cells. It can be induced on splenic B cells by in vitro polyclonal activation such as LPS treatment. 3H5 mAb is reported to block the costimulatory function of rat CD80 and to immunoprecipitate CD80 from Lewis-S1 cell lysates.

Flow Cytometry

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD80
Applications Flow Cytometry
Classification Monoclonal
Clone 3H5
Concentration 0.5mg/mL
Conjugate Biotin
Description B7-1
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Rat HTLV-1-transformed T-cell line Lewis-S1
Purification Method Affinity Purified
Quantity 0.5 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Rat
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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For Research Use Only.

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