CD80 Mouse anti-Human, PE, Clone: L307.4, BD

Catalog No.	Quantity
BDB340294	50 Tests

Catalog No. BDB340294 Supplier BD Biosciences Supplier No. 340294

Description

Mouse Monoclonal Antibody

Reacts with B7/BB1, a 60kDa transmembrane glycoprotein which was clustered as CD80 in the Fifth International Workshop on Human Leukocyte Differentiation Antigens. CD80, a member of the Ig supergene family, is expressed on activated B cells, macrophages, and dendritic cells. It is the ligand for two molecules expressed on T cells, CD28 and CD152 (CTLA-4). CD80 is also expressed on activated CD4+ and CD8+ T cells, appearing late after activation suggesting that activated T cells may be capable of autocrine costimulation via the CD28 activation pathway. The binding of CD28 by anti-CD28 or by CD80 results in T-cell activation and a signal for IL-2 production.

Specifications

• Antigen: CD80
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: L307.4
• Concentration: 3.2μg/mL
• Conjugate: PE
• Formulation: Phosphate buffered saline with gelatin and 0.1% sodium azide.
• Host Species: Mouse
• Immunogen: Human B7-transfected L cells
• Purification Method: Affinity Purified
• Quantity: 50 Tests
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human
• Content And Storage: Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.
• Isotype: IgG1 κ

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.