CD86 Mouse anti-Human, Brilliant Violet 421, Clone: 2331 (FUN-1), BD

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
BDB562433	BD Biosciences 562433	25 Tests
BDB562432	BD Biosciences 562432	100 Tests

Description

The 2331 (FUN-1) monoclonal antibody specifically recognizes a 75 kDa transmembrane cell surface protein, CD86 (B70/B7-2), expressed primarily on monocytes, dendritic cells and activated B cells. Competitive binding assays demonstrate that, while both 2331 (FUN-1) and IT2.2 (anti-CD86, Cat. No. 555663) antibodies specifically recognize the same molecule, they react with different epitopes. CD86 is the second ligand for CD28 and CTLA-4 and may play an important role in co-stimulation of T cells in primary immune response. The 2331 (FUN-1) antibody blocks the costimulatory activity of CD86 when tested in functional studies.The antibody was conjugated to Brilliant Violet 421 and has been developed in collaboration with Sirigen. With an Ex Max of 407-nm and Em Max at 421-nm, Brilliant Violet 421 can be excited by the violet laser and detected in the standard Pacific Blue filter set (eg, 450/50-nm filter). Brilliant Violet 421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.

Host Species: Mouse
Clone: 2331 (FUN-1)
Isotype: IgG1, κ
Species Reactivity: Human

Flow Cytometry

Specifications

• Antigen: CD86
• Applications: Flow Cytometry
• Conjugate: Brilliant Violet 421
• Regulatory Status: RUO
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Isotype: IgG1 κ
• Purification Method: Affinity Purified
• Description: B7.2; B7-2; B-lymphocyte activation antigen B7-2; B70; BU63; CD28LG2; LAB72

• Clone: 2331 (FUN-1)
• Classification: Monoclonal
• Host Species: Mouse
• Target Species: Human
• Immunogen: Human HBL-1 Cell Line
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

For Research Use Only.