CD86 Mouse anti-Rat, PE, Clone: 24F, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 551396

Catalog No. BDB551396

Description

The 24F antibody reacts with CD86 (B7-2), a member of the Ig superfamily of transmembrane proteins. CD86, a ligand for CD28 and CD152 (CTLA-4), is one of the accessory molecules that plays an important role in T cell-B cell costimulatory interactions. CD86 is predominantly expressed on antigen-presenting cells. It can be upregulated on splenic B cells by in vitro polyclonal activation, such as LPS treatment. 24F mAb is reported to block the costimulatory function of rat CD86 and to immunoprecipitate CD86 from Lewis-S1 cell lysates. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Host Species: Mouse
Clone: 24F
Isotype: IgG1 κ
Species Reactivity: Rat
Immunogen: HTLV-1-transformed rat T-cell line Lewis-S1

Flow Cytometry

Specifications

• Antigen: CD86
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Description: B7-2
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Applications: Flow Cytometry
• Clone: 24F
• Conjugate: PE
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: HTLV-1-transformed rat T-cell line Lewis-S1
• Quantity: 0.1 mg
• Research Discipline: Immunology
• Target Species: Rat
• Isotype: IgG1 κ

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.