CD90.1 Mouse anti-Rat/Mouse, FITC, Clone: HIS51, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 554894

Catalog No. BDB554894

Description

The HIS51 antibody reacts with the rat Thy-1 antigen (CD90) expressed by hematopoietic stem cells, early myeloid and erythroid cells, immature B lymphocytes in the bone marrow and peripheral lymphoid organs, thymocytes, recent thymic emigrants (a subset of CD45RCperipheral T cells), neurons, glomerular mesangial cells, endothelium at inflammatory sites, mast cells, and bone marrow-derived dendritic cells. Rat dendritic epidermal T cells (DEC) are Thy-1-negative. CD90 is a GPI-anchored membrane glycoprotein of the Ig superfamily which is involved in signal transduction. In addition, there is evidence in the mouse that CD90 mediates adhesion of thymocytes to thymic stroma. HIS51 antibody cross-reacts with the mouse Thy-1.1 alloantigen of the AKR/J and PL strains, but not Thy-1.2 found on most strains. In the mouse, CD90 is found on thymocytes, most peripheral T lymphocytes, some intraepithelial T lymphocytes (IEL, DEC), hematopoietic stem cells, and neurons, but not B lymphocytes.

Flow Cytometry

Specifications

• Antigen: CD90.1
• Classification: Monoclonal
• Concentration: 0.5mg/mL
• Description: Thy-1/Thy-1.1
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Applications: Flow Cytometry
• Clone: HIS51
• Conjugate: FITC
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: Rat bone marrow cells
• Quantity: 0.5 mg
• Research Discipline: Immunology
• Target Species: Mouse, Rat
• Isotype: IgG2a κ

For Research Use Only.