CD90.1 Mouse, PE-Cy7, Clone: OX-7 (also known as OX7), BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 561404

Catalog No. BDB561404

Description

CD90 (Thy-1) is a GPI-anchored membrane glycoprotein of the Ig superfamily which is involved in signal transduction. The OX-7 monoclonal antibody specifically binds to rat CD90 reported to be expressed by hematopoietic stem cells, early myeloid and erythroid cells, immature B lymphocytes in the bone marrow and peripheral lymphoid organs, thymocytes, recent thymic emigrants (a subset of CD45RC- peripheral T lymphocytes), neurons, glomerular mesangial cells, endothelium at inflammatory sites, mast cells, and dendritic cells. Rat dendritic epidermal T cells (DEC) have been reported to be CD90 (Thy-1) negative, unlike those of the mouse.

The OX-7 clone has been reported to crossreact with the mouse CD90.1 (Thy-1.1) alloantigen of the AKR/J and PL strains, but not CD90.2 (Thy-1.2) found on many mouse strains. In the mouse, CD90 is found on thymocytes, most peripheral T lymphocytes, some intraepithelial T lymphocytes (IEL, DEC), hematopoietic stem cells, and neurons, but not B lymphocytes. In addition, there is evidence that CD90 mediates adhesion of mouse thymocytes to mouse thymic stroma. The OX-7 clone has also been reported to crossreact with rabbit and guinea pig thymus, brain, and intestine.

Specifications

• Antigen: CD90.1
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Description: Rat Thy-1; Mouse Thy-1.1
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Guinea Pig, Mouse, Rabbit, Rat
• Isotype: IgG1 κ

• Applications: Flow Cytometry
• Clone: OX-7 (also known as OX7)
• Conjugate: PE-Cyanine7
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: Rat Thymocyte Thy-1 Antigen
• Quantity: 50 μg
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.