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CD90.2 Rat anti-Mouse, Unlabeled, Clone: 53-2.1, BD

Catalog No. BDB553000 Shop All BD Biosciences Products
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BDB553000 0.5 mg
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Catalog No. BDB553000 Supplier BD Biosciences Supplier No. 553000
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Description

Rat Monoclonal Antibody

The 53-2.1 antibody reacts with the CD90.2 (Thy-1.2) alloantigen on thymocytes, most peripheral T lymphocytes, some intraepithelial T lymphocytes (IEL, DEC), epithelial cells, fibroblasts, neurons, hematopoietic stem cells, but not B lymphocytes, of most mouse strains. mAb 53-2.1 has been reported not to cross-react with Thy-1.1 (e.g., AKR/J, PL), or with rat Thy-1. CD90 is a GPI-anchored membrane glycoprotein of the Ig superfamily which is involved in signal transduction. In addition, there is evidence that CD90 mediates adhesion of
thymocytes to thymic stroma. mAb 53-2.1 has been reported to block the binding of anti-mouse CD90.2 clone 30-H12 (Cat. No. 553009) to immobilized thymocyte membranes.
This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD90.2
Applications Flow Cytometry
Classification Monoclonal
Clone 53-2.1
Concentration 0.5mg/mL
Conjugate Unconjugated
Description Thy-1.2; T25; Thymus cell antigen 1, theta
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen Mouse Thymus / Spleen
Purification Method Affinity Purified
Quantity 0.5 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C
Isotype IgG2a κ
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For Research Use Only.

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