CD90.2 Rat anti-Mouse, PE, Clone: 53-2.1, BD

Rat Monoclonal Antibody

Supplier:  BD Biosciences 553006

Catalog No. BDB553006

Description

The 53-2.1 antibody reacts with the CD90.2 (Thy-1.2) alloantigen on thymocytes, most peripheral T lymphocytes, some intraepithelial T lymphocytes (IEL, DEC), epithelial cells, fibroblasts, neurons, hematopoietic stem cells, but not B lymphocytes, of most mouse strains. mAb 53-2.1 has been reported not to cross-react with Thy-1.1 (e.g., AKR/J, PL), or with rat Thy-1. CD90 is a GPI-anchored membrane glycoprotein of the Ig superfamily which is involved in signal transduction. In addition, there is evidence that CD90 mediates adhesion of
thymocytes to thymic stroma. mAb 53-2.1 has been reported to block the binding of anti-mouse CD90.2 clone 30-H12 (Cat. No. 553009) to immobilized thymocyte membranes. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Host Species: Rat
Clone: 53-2.1
Isotype: IgG2a κ
Species Reactivity: Mouse
Immunogen: Mouse Thymus / Spleen

Flow Cytometry

Specifications

• Antigen: CD90.2
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Description: Thy-1.2; T25; Thymus cell antigen 1, theta
• Host Species: Rat
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Applications: Flow Cytometry
• Clone: 53-2.1
• Conjugate: PE
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: Mouse Thymus / Spleen
• Quantity: 0.2 mg
• Research Discipline: Immunology
• Target Species: Mouse
• Isotype: IgG2a κ

For Research Use Only.