CD91 Mouse anti-Human, FITC, Clone: A2MR-A2, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 550496

Catalog No. BDB550496

Description

Reacts with a 600kDa, type I membrane single protein, also known as the α2 Macroglobulin (α2M) receptor/low density lipoprotein (LDL) receptor. The single chain receptor undergoes cleavage, shortly after synthesis, into the 85kDa transmembrane β chain that non-covalently binds to the extracellular 500-515kDa a chain. It has a broad cellular distribution, but in the hematopoietic system it is expressed on monocyte lineage cells. The α2M/LDL receptor mediates endocytosis of a variety of ligands including α2M-proteinase complexes, plasminogen activators in complex with plasminogen activator inhibitor, Pseudomonas Exotoxin A. Ligand binding to α2M/LDL receptor is followed by rapid transport of the ligand to lysosomes for degradation.

Host Species: Mouse
Clone: A2MR-α2
Isotype: IgG1 κ
Species Reactivity: Human

Flow Cytometry

Specifications

• Antigen: CD91
• Classification: Monoclonal
• Conjugate: FITC
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Applications: Flow Cytometry
• Clone: A2MR-A2
• Description: Alpha-2-macroglobulin receptor; α2MR; LRP-1; LDL Receptor-Related Protein-1
• Host Species: Mouse
• Quantity: 100 Tests
• Research Discipline: Immunology
• Target Species: Human
• Isotype: IgG1 κ

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.